Symbol
Name
ID

Ift140
intraflagellar transport 140
MGI:2146906

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hypogonadism	Abnormal testis morphology
Disease(s) Associated with IFT140	Hypogonadism	Abnormal testis morphology
retinitis pigmentosa

Mouse Phenotypes

reproductive system phenotype

abnormal sperm flagellum morphology

abnormal outer dense fiber morphology

abnormal sperm axoneme morphology

abnormal sperm end piece morphology

abnormal sperm mitochondrial sheath morphology

abnormal sperm fibrous sheath morphology

kinked sperm flagellum

short sperm flagellum

oligozoospermia

teratozoospermia

abnormal sperm head morphology

abnormal sperm nucleus morphology

abnormal spermatid morphology

abnormal manchette morphology

decreased sperm progressive motility

asthenozoospermia

immotile sperm

abnormal spermiogenesis

abnormal spermiation

male infertility

impaired fertilization

Availability

Mouse Genotype

Ift140^{tm1c(KOMP)Wtsi}/Ift140^{tm1c(KOMP)Wtsi}
Tg(Stra8-icre)1Reb/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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